Also in the News: Even Low Doses of Radiation in Childhood May Raise Breast Cancer Risk
More childhood cancer survivors who received radiation to the chest as part of cancer treatment may be at risk of breast cancer later in life than previously thought, according to data presented at the American Society of Clinical Oncology annual meeting
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Dr. Chaya Moskowitz of Memorial Sloan-Kettering Cancer Center presented data from more than 1,200 women participating in the Childhood Cancer Survivor Study who received radiation to the chest as children, adolescents, or young adults. She and her colleagues found that nearly one-quarter of the women who received 20 gray (Gy), a unit of absorbed dose, of radiation or more developed breast cancer by age 50, with about half of those developing the disease before age 40. In addition, 7 percent of women who received lower doses of radiation—10 to 19 Gy—developed breast cancer by the age of 40. In contrast, a 20-year-old woman in the general population has a less than 2 percent chance of developing breast cancer by age 50.
Current guidelines for childhood cancer survivors generally recommend early screening—with breast MRI— only for patients who received 20 Gy of radiation or more; the guidelines do not recommend earlier screening for women who received lower doses.
More childhood cancer survivors who received radiation to the chest as part of cancer treatment may be at risk of breast cancer later in life than previously thought, according to data presented at the American Society of Clinical Oncology annual meeting
.Dr. Chaya Moskowitz of Memorial Sloan-Kettering Cancer Center presented data from more than 1,200 women participating in the Childhood Cancer Survivor Study who received radiation to the chest as children, adolescents, or young adults. She and her colleagues found that nearly one-quarter of the women who received 20 gray (Gy), a unit of absorbed dose, of radiation or more developed breast cancer by age 50, with about half of those developing the disease before age 40. In addition, 7 percent of women who received lower doses of radiation—10 to 19 Gy—developed breast cancer by the age of 40. In contrast, a 20-year-old woman in the general population has a less than 2 percent chance of developing breast cancer by age 50.
Current guidelines
for childhood cancer survivors generally recommend early screening—with breast MRI— only for patients who received 20 Gy of radiation or more; the guidelines do not recommend earlier screening for women who received lower doses.
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